Description

5-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused indole and tetrahydropyridine structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) targeted therapeutics and novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up of potential APIs, particularly for CNS disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Research: Employed in academic and industrial research to study receptor-ligand interactions and biochemical mechanisms.

Basic Information

Product Name	5-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole
CAS No.	885273-31-4
Molecular Formula	C14H16N2
Molecular Weight	212.29 g/mol
Synonyms	1H-Indole, 5-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-; 5-(1-Methyl-4-piperidinyl)indole; 5-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole; 5-(N-Methyl-1,2,3,6-tetrahydropyridin-4-yl)indole; 5-(1-Methyl-δ³-piperiden-4-yl)indole; 5-(1-Methyl-1,2,3,6-tetrahydro-4-pyridyl)indole
EINECS	Contact for details

Quality Control

Our 5-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.