Description

4-(1H-Indol-5-Yl)-Tetrahydro-Thiopyran-4-Ol CAS NO 885273-20-1 is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines indole and thiopyran motifs. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly targeting central nervous system (CNS) disorders. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for building complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic structure.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and target validation.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under GMP-like conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.
• Academic Research: Utilized in university and institutional labs for pioneering synthetic methodology and bioorganic chemistry studies.

Basic Information

Product Name	4-(1H-Indol-5-Yl)-Tetrahydro-Thiopyran-4-Ol
CAS No.	885273-20-1
Molecular Formula	C13H15NOS
Molecular Weight	233.33 g/mol
Synonyms	4-(1H-Indol-5-yl)tetrahydro-2H-thiopyran-4-ol; 4-(1H-Indol-5-yl)thiane-4-ol; 4-(5-Indolyl)-4-hydroxythiane; 4-Hydroxy-4-(5-indolyl)thiane; Tetrahydro-4-(1H-indol-5-yl)-2H-thiopyran-4-ol; 4-(1H-Indol-5-yl)thiopyran-4-ol (tetrahydro); 885273-20-1
EINECS	Contact for details

Quality Control

Our 4-(1H-Indol-5-Yl)-Tetrahydro-Thiopyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.