Description

6-(3,6-Dihydro-2H-Thiopyran-4-Yl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold that combines indole and thiopyran moieties. This compound is of significant value for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization due to its privileged heterocyclic structure.
• CNS Drug Development: A key precursor for compounds being investigated for neurological disorders, leveraging the indole core's bioactivity.
• Oncology Research: Employed in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke molecules for client R&D.

Basic Information

Product Name	6-(3,6-Dihydro-2H-Thiopyran-4-Yl)-1H-Indole
CAS No.	885273-10-9
Molecular Formula	C13H13NS
Molecular Weight	215.31 g/mol
Synonyms	6-(3,6-Dihydro-2H-thiopyran-4-yl)-1H-indole; 1H-Indole, 6-(3,6-dihydro-2H-thiopyran-4-yl)-; 4-(1H-Indol-6-yl)-3,6-dihydro-2H-thiopyran; 6-(3,6-Dihydro-2H-thiopyran-4-yl)indole; 885273-10-9
EINECS	Contact for details

Quality Control

Our 6-(3,6-Dihydro-2H-Thiopyran-4-Yl)-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines for the production of advanced intermediates, and specifications can be aligned with client requirements for specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.