Description

5-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indazole is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of new therapeutic agents targeting the central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in neuroscience and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Employed in vitro and in vivo to study biological pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of investigational drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	5-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indazole
CAS No.	885272-72-0
Molecular Formula	C13H15N3
Molecular Weight	213.28 g/mol
Synonyms	5-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole; 1H-Indazole, 5-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-; 5-(1-Methyl-4-piperidinyl)-1H-indazole (tautomeric form); 885272-72-0; 5-(1-Methyl-1,2,3,6-tetrahydro-4-pyridyl)indazole; 5-(N-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole
EINECS	Contact for details

Quality Control

Our 5-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.