Description

4-(1H-Indazol-5-Yl)-Tetrahydro-Thiopyran-4-Ol CAS NO 885272-66-2 is a high-value, heterocyclic organic compound featuring a fused indazole and thiopyranol structure. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs, particularly those targeting kinase inhibition and other complex biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Biochemical Tool Compound: Employed in biological assays to study enzyme function and cellular signaling pathways.
• Organic Synthesis: Acts as a versatile precursor for constructing more complex heterocyclic systems in academic and industrial research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	4-(1H-Indazol-5-Yl)-Tetrahydro-Thiopyran-4-Ol
CAS No.	885272-66-2
Molecular Formula	C12H14N2OS
Molecular Weight	234.32 g/mol
Synonyms	4-(1H-Indazol-5-yl)tetrahydro-2H-thiopyran-4-ol; 4-(1H-Indazol-5-yl)thiacyclohexan-4-ol; Tetrahydro-4-(1H-indazol-5-yl)-2H-thiopyran-4-ol; 4-(1H-Indazol-5-yl)thiane-4-ol; 885272-66-2; 4-(1H-Indazol-5-yl)tetrahydro-4-thiopyranol
EINECS	Contact for details

Quality Control

Our production of 4-(1H-Indazol-5-Yl)-Tetrahydro-Thiopyran-4-Ol adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications from HPLC, NMR, and mass spectrometry are provided to guarantee traceability and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.