Description

4-(1H-Indazol-5-Yl)-Tetrahydro-Pyran-4-Ol CAS NO 885272-57-1 is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines indazole and tetrahydropyran motifs. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in oncology and central nervous system (CNS) disease areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Employed in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Serves as a building block for compounds targeting neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for chemical biology and novel heterocyclic compound synthesis.

Basic Information

Product Name	4-(1H-Indazol-5-Yl)-Tetrahydro-Pyran-4-Ol
CAS No.	885272-57-1
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	4-(1H-Indazol-5-yl)oxan-4-ol; 4-(1H-Indazol-5-yl)tetrahydro-2H-pyran-4-ol; Tetrahydro-2H-pyran-4-ol, 4-(1H-indazol-5-yl)-; 4-(1H-Indazol-5-yl)-4-hydroxytetrahydropyran; 4-(1H-Indazol-5-yl)tetrahydropyran-4-ol; 4-(1H-Indazol-5-yl)-4-hydroxy-tetrahydropyran; 885272-57-1; 4-(1H-Indazol-5-yl)-tetrahydro-pyran-4-ol
EINECS	Contact for details

Quality Control

Our 4-(1H-Indazol-5-Yl)-Tetrahydro-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.