Description

6-(1-Methyl-Piperidin-4-Yl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate featuring a unique indazole-piperidine hybrid scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of targeted therapies, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small-molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for developing potent and selective kinase inhibitors due to the indazole moiety's ability to mimic adenine.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties of lead compounds.
• Biochemical Probe Development: Employed in creating chemical probes for investigating biological processes and validating novel drug targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development programs.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	6-(1-Methyl-Piperidin-4-Yl)-1H-Indazole
CAS No.	885272-33-3
Molecular Formula	C13H17N3
Molecular Weight	215.30 g/mol
Synonyms	6-(1-Methyl-4-piperidyl)-1H-indazole; 1H-Indazole, 6-(1-methyl-4-piperidinyl)-; 6-(1-Methylpiperidin-4-yl)-1H-indazole; 6-(1-Methyl-4-piperidinyl)indazole; 6-(N-Methyl-4-piperidyl)indazole; 885272-33-3; 6-(1-Methylpiperidin-4-yl)indazole
EINECS	Contact for details

Quality Control

Our 6-(1-Methyl-Piperidin-4-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	≤ 3.0% total
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.