Description

3-Pyrrolidin-2-Yl-Indole-1-Carboxylic Acid tert-Butyl Ester is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines indole and pyrrolidine motifs protected by a tert-butyl ester group. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological receptors and enzymes.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential insecticidal or herbicidal properties.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological development in heterocyclic and peptide chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and process development projects.

Basic Information

Product Name	3-Pyrrolidin-2-Yl-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	885272-31-1
Molecular Formula	C17H22N2O2
Molecular Weight	286.37 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-(2-pyrrolidinyl)-, 1,1-dimethylethyl ester; tert-Butyl 3-(pyrrolidin-2-yl)-1H-indole-1-carboxylate; 3-(2-Pyrrolidinyl)-1H-indole-1-carboxylic acid tert-butyl ester; 3-(Pyrrolidin-2-yl)indole-1-carboxylic acid tert-butyl ester; BOC-3-(2-Pyrrolidinyl)indole; 885272-31-1
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidin-2-Yl-Indole-1-Carboxylic Acid tert-Butyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.