Description

1H-Indole-6-Carbothioic Acid Amide is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the indole scaffold's bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions.
• Material Science: Potential building block for advanced organic electronic materials and functional polymers.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies and the discovery of new chemical entities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1H-Indole-6-Carbothioic Acid Amide
CAS No.	885272-19-5
Molecular Formula	C9H8N2S
Molecular Weight	176.24 g/mol
Synonyms	6-Carbamothioyl-1H-indole; Indole-6-carbothioamide; 1H-Indole-6-thiocarboxamide; 6-Thiocarbamoylindole; 6-(Aminothioxomethyl)-1H-indole; 885272-19-5; 6-Indolecarbothioamide
EINECS	Contact for details

Quality Control

Our 1H-Indole-6-Carbothioic Acid Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material may be light-sensitive and/or hygroscopic; handle and store under an inert atmosphere if specified for your grade.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.