Description

6-(Benzothiophen-2-Yl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in modern medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Used extensively in research for constructing potential kinase inhibitors due to its privileged indazole-benzothiophene scaffold.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D labs.
• Biochemical Probe Synthesis: Employed in creating chemical probes for studying biological processes and target validation.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for use in custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	6-(Benzothiophen-2-Yl)-1H-Indazole
CAS No.	885272-15-1
Molecular Formula	C15H10N2S
Molecular Weight	250.32 g/mol
Synonyms	6-(1-Benzothiophen-2-yl)-1H-indazole; 6-(Benzothiophen-2-yl)-1H-indazole; 1H-Indazole, 6-(2-benzothienyl)-; 6-(2-Benzothienyl)-1H-indazole; 6-(Benzothiophen-2-yl)indazole; 885272-15-1; BTI; 6-(Benzothiophen-2-yl)-1H-indazole
EINECS	Contact for details

Quality Control

Our 6-(Benzothiophen-2-Yl)-1H-Indazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.