Description

6-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting oncology, inflammation, and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Serves as a starting material for developing tool compounds to study biological pathways and target validation.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for bespoke chemical synthesis projects.
• Library Synthesis: Used to generate diverse compound libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	6-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indazole
CAS No.	885271-92-1
Molecular Formula	C12H12N2O
Molecular Weight	200.24 g/mol
Synonyms	6-(3,6-Dihydro-2H-pyran-4-yl)-1H-indazole; 1H-Indazole, 6-(3,6-dihydro-2H-pyran-4-yl)-; 6-(3,6-Dihydro-2H-pyran-4-yl)indazole; 6-(3,6-Dihydro-2H-pyran-4-yl)-1H-indazole; 885271-92-1; 6-(3,6-Dihydro-2H-pyran-4-yl)indazole; 4-(1H-Indazol-6-yl)-3,6-dihydro-2H-pyran
EINECS	Contact for details

Quality Control

Our 6-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.