Description

6-Bromo-3-Chloro-1H-Indazole is a high-value halogenated indazole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, multi-functional scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel drug candidates, especially in kinase inhibitor programs and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents and pesticides.
• Material Science: Potential use in the development of organic electronic materials and advanced polymers due to its heterocyclic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	6-Bromo-3-Chloro-1H-Indazole
CAS No.	885271-78-3
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	6-Bromo-3-chloro-1H-indazole; 3-Chloro-6-bromo-1H-indazole; 1H-Indazole, 6-bromo-3-chloro-; 6-Bromo-3-chloroindazole; 885271-78-3; AKOS005258213; BRN 15028478; CS-W009767; SCHEMBL15549027; ZINC000257019773
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-1H-Indazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch and supplied upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.