Description

1-Boc-3-Bromo-5-Fluoro-Indazole is a high-purity, multi-functional heterocyclic building block of significant importance in modern organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of complex pharmaceutical molecules and advanced agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel indazole-based scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated indazole core.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study enzyme function and biological pathways.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	1-Boc-3-Bromo-5-Fluoro-Indazole
CAS No.	885271-57-8
Molecular Formula	C₁₂H₁₂BrFN₂O₂
Molecular Weight	315.14 g/mol
Synonyms	tert-Butyl 3-bromo-5-fluoro-1H-indazole-1-carboxylate; 3-Bromo-5-fluoro-1H-indazole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-bromo-5-fluoroindazole; 1-Boc-3-bromo-5-fluoro-1H-indazole; Boc-3-Br-5-F-indazole; 885271-57-8
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Bromo-5-Fluoro-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.