Description

5-Methoxy-2-(5-Nitro-1H-Indol-2-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel indole-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis: Acts as a versatile precursor for constructing complex heterocyclic systems in fine chemical production.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its specific indole-nitrogen functionality.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Studies: Employed in advanced organic chemistry and pharmacology research within university laboratories.

Basic Information

Product Name	5-Methoxy-2-(5-Nitro-1H-Indol-2-Yl)Benzoic Acid
CAS No.	885271-46-5
Molecular Formula	C₁₆H₁₂N₂O₅
Molecular Weight	312.28 g/mol
Synonyms	2-(5-Methoxy-2-carboxyphenyl)-5-nitro-1H-indole; 5-Nitro-2-(2-carboxy-4-methoxyphenyl)indole; 5-Methoxy-2-(5-nitro-1H-indol-2-yl)benzoic acid; Benzoic acid, 5-methoxy-2-(5-nitro-1H-indol-2-yl)-; 885271-46-5; 5-Methoxy-2-(5-nitroindol-2-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our production of 5-Methoxy-2-(5-Nitro-1H-Indol-2-Yl)Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the rigorous standards required for pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.