Description

4-(Aminomethyl)-1,2-Dihydroisoquinolin-3(4H)-One is a versatile heterocyclic organic compound featuring a fused isoquinolinone core with an aminomethyl functional group. This unique structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Organic Synthesis Building Block: Used to construct complex nitrogen-containing heterocycles, leveraging its reactive aminomethyl group for further functionalization.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Agrochemical Intermediate: Potential use in the synthesis of novel pesticides or herbicides, given its heterocyclic scaffold.
• Ligand Synthesis: Can be utilized to develop novel chelating agents or ligands for catalysis and material science applications.

Basic Information

Product Name	4-(Aminomethyl)-1,2-Dihydroisoquinolin-3(4H)-One
CAS No.	885270-88-2
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	4-(Aminomethyl)-3,4-dihydro-1H-isoquinolin-3-one; 4-(Aminomethyl)-1,2-dihydro-3H-isoquinolin-3-one; 3(4H)-Isoquinolinone, 4-(aminomethyl)-1,2-dihydro-; 4-(Aminomethyl)isoquinolin-3(4H)-one; 1,2-Dihydro-4-(aminomethyl)isoquinolin-3(4H)-one; 4-Aminomethyl-1,2-dihydroisoquinolin-3-one
EINECS	Contact for details

Quality Control

Our production of 4-(Aminomethyl)-1,2-Dihydroisoquinolin-3(4H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our facilities operate under cGMP guidelines suitable for pharmaceutical intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.