Description

1-Boc-4-Aminoindole is a protected aminoindole derivative, a crucial building block in modern organic synthesis. Its primary value lies in providing a versatile and reactive amine group, protected by the acid-labile tert-butoxycarbonyl (Boc) group, for the controlled construction of complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel indole-based active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with indole core structures.
• Peptidomimetics Research: Used to incorporate indole scaffolds into peptide analogs to enhance stability and biological activity.
• Material Science: Intermediate for synthesizing functionalized indoles used in organic electronic materials and dyes.
• Academic & R&D: Fundamental reagent in medicinal chemistry labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	1-Boc-4-Aminoindole
CAS No.	885270-30-4
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-1H-indol-4-amine; 4-Amino-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-amino-1H-indole-1-carboxylate; 4-Amino-1-Boc-indole; 1-Boc-4-aminoindole; N-Boc-4-aminoindole; 1-(tert-Butoxycarbonyl)-4-aminoindole; Boc-4-Aminoindole
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Aminoindole is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.