Description

tert-Butyl Indolin-7-Yl-Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific carbamate-protected indoline structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules and investigational new chemical entities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• API Development: Serves as a protected precursor in the scalable production route development for potential Active Pharmaceutical Ingredients.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing indoline-based heterocyclic compounds and exploring novel chemical reactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects, supporting outsourcing needs in the pharmaceutical and biotechnology sectors.

Basic Information

Product Name	tert-Butyl Indolin-7-Yl-Carbamate
CAS No.	885270-12-2
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	7-[(tert-Butoxycarbonyl)amino]indoline; 1,2,3,4-Tetrahydro-7-[(2-methyl-2-propanyloxy)carbonyl]amino]-1H-indole; tert-Butyl (2,3-dihydro-1H-indol-7-yl)carbamate; 7-((tert-Butoxycarbonyl)amino)indoline; Boc-7-aminoindoline; N-Boc-7-aminoindoline; tert-Butyl N-(2,3-dihydro-1H-indol-7-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl Indolin-7-Yl-Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to minimize potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.