Description

3-(1H-Indazol-3-Yl)-3-Oxo-Propionic Acid Ethyl Ester is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its indazole core, a privileged scaffold in medicinal chemistry, which makes it a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and combinatorial chemistry to develop new chemical entities (NCEs) and explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.
• Biochemical Tool Compound: Used in academic and industrial research to study biological processes and enzyme functions.

Basic Information

Product Name	3-(1H-Indazol-3-Yl)-3-Oxo-Propionic Acid Ethyl Ester
CAS No.	885269-76-1
Molecular Formula	C₁₂H₁₂N₂O₃
Molecular Weight	232.24 g/mol
Synonyms	Ethyl 3-(1H-indazol-3-yl)-3-oxopropanoate; 3-Oxo-3-(1H-indazol-3-yl)propanoic acid ethyl ester; 3-(1H-Indazol-3-yl)-3-oxopropionic acid ethyl ester; 1H-Indazole-3-propanoic acid, 3-oxo-, ethyl ester; Ethyl 3-(1H-indazol-3-yl)-3-oxopropionate; 3-(1H-Indazol-3-yl)-3-oxo-propionic acid ethyl ester; 885269-76-1
EINECS	Contact for details

Quality Control

Our production of 3-(1H-Indazol-3-Yl)-3-Oxo-Propionic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to in-house specifications aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.