Description

7'-Bromo-2',3'-dihydro-1'H-spiro[cyclopentane-1,4'-isoquinoline] CAS NO 885269-43-2 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and brominated isoquinoline structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for creating novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and protein functions.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Process Chemistry Development: Used in scaling up synthetic routes for potential clinical candidates during process research and development.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	7'-Bromo-2',3'-dihydro-1'H-spiro[cyclopentane-1,4'-isoquinoline]
CAS No.	885269-43-2
Molecular Formula	C₁₃H₁₄BrN
Molecular Weight	248.16 g/mol
Synonyms	7'-Bromo-1'H-spiro[cyclopentane-1,4'-isoquinoline]-2',3'-dihydro; 7'-Bromospiro[cyclopentane-1,4'-isoquinoline]-2',3'-dihydro; 7-Bromo-2,3-dihydro-1H-spiro[cyclopentane-1,4-isoquinoline]; 7-Bromo-2,3-dihydrospiro[cyclopentane-1,4-isoquinoline]; 7-Bromo-2,3-dihydro-1H-spiro[cyclopentane-1,4-isoquinoline]; Spiro[cyclopentane-1,4'-isoquinoline], 7'-bromo-2',3'-dihydro-; 885269-43-2
EINECS	Contact for details

Quality Control

Our 7'-Bromo-2',3'-dihydro-1'H-spiro[cyclopentane-1,4'-isoquinoline] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.