Description

2-(8-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol is a high-purity, advanced pharmaceutical intermediate characterized by its brominated tetrahydroisoquinoline core structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Alkaloid Analog Development: Serves as a synthetic building block for creating novel tetrahydroisoquinoline-based alkaloid analogs with modified biological activity.
• Chemical Biology Probes: Utilized in the development of chemical probes to study enzyme function and biological mechanisms.

Basic Information

Product Name	2-(8-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol
CAS No.	885268-69-9
Molecular Formula	C₁₁H₁₄BrNO
Molecular Weight	256.14 g/mol
Synonyms	8-Bromo-4-(2-hydroxyethyl)-1,2,3,4-tetrahydroisoquinoline; 2-(8-Bromo-3,4-dihydro-1H-isoquinolin-4-yl)ethan-1-ol; 4-(2-Hydroxyethyl)-8-bromo-1,2,3,4-tetrahydroisoquinoline; 8-Bromotetrahydroisoquinoline-4-ethanol; 885268-69-9; BR-THIQ-EtOH
EINECS	Contact for details

Quality Control

Our 2-(8-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.