Description

2-(6-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol is a high-purity brominated tetrahydroisoquinoline derivative, a crucial advanced pharmaceutical intermediate. This compound matters for its role as a sophisticated building block in the synthesis of complex bioactive molecules, offering a strategic point for further functionalization. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel therapeutic agents.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• CNS Drug Development: Used in the synthesis of potential candidates targeting neurological disorders, leveraging the tetrahydroisoquinoline core structure.
• Oncological Research: Employed as a building block for creating compounds with potential anti-cancer activity.
• Chemical Synthesis: Utilized in organic synthesis for the introduction of the bromo-tetrahydroisoquinoline moiety into more complex molecular architectures.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-(6-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol
CAS No.	885268-59-7
Molecular Formula	C₁₁H₁₄BrNO
Molecular Weight	256.14 g/mol
Synonyms	2-(6-Bromo-3,4-dihydro-1H-isoquinolin-4-yl)ethanol; 4-(2-Hydroxyethyl)-6-bromo-1,2,3,4-tetrahydroisoquinoline; 6-Bromo-4-(2-hydroxyethyl)-1,2,3,4-tetrahydroisoquinoline; 2-(6-Bromotetrahydroisoquinolin-4-yl)ethan-1-ol; 6-Bromo-THIQ-ethanol derivative; Brominated tetrahydroisoquinoline ethanol
EINECS	Contact for details

Quality Control

Our 2-(6-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.