Description

2-(5-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol is a high-purity brominated tetrahydroisoquinoline derivative, a crucial advanced pharmaceutical intermediate. This compound matters for its role as a sophisticated building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential candidates for central nervous system (CNS) and oncology applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds due to its reactive bromine and ethanol functional groups.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory synthesis and method development in organic chemistry.
• Pre-clinical Development: Utilized in the synthesis of compounds for pharmacological screening and pre-clinical testing phases.

Basic Information

Item	Details
Product Name	2-(5-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol
CAS No.	885268-57-5
Molecular Formula	C₁₁H₁₄BrNO
Molecular Weight	256.14 g/mol
Synonyms	5-Bromo-4-(2-hydroxyethyl)-1,2,3,4-tetrahydroisoquinoline; 2-(5-Bromo-3,4-dihydro-1H-isoquinolin-4-yl)ethan-1-ol; 4-(2-Hydroxyethyl)-5-bromo-1,2,3,4-tetrahydroisoquinoline; 5-Bromo-4-(2-hydroxyethyl)-1,2,3,4-tetrahydroisoquinoline; 885268-57-5; 2-(5-Bromo-1,2,3,4-tetrahydro-4-isoquinolinyl)ethanol
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your research and development documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.