Description

2-(5-Chloro-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmacologically active molecules, offering a versatile scaffold for medicinal chemistry research. Pharmaceutical R&D and fine chemical synthesis laboratories need this high-purity intermediate to streamline the creation of novel compounds targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex tetrahydroisoquinoline derivatives with tailored properties.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and development of proprietary chemical entities.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	2-(5-Chloro-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol
CAS No.	885268-55-3
Molecular Formula	C₁₁H₁₄ClNO
Molecular Weight	211.69 g/mol
Synonyms	4-(2-Hydroxyethyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline; 5-Chloro-4-(2-hydroxyethyl)-1,2,3,4-tetrahydroisoquinoline; 2-(5-Chloro-3,4-dihydro-1H-isoquinolin-4-yl)ethan-1-ol; 5-Chloro-4-(2-hydroxyethyl)-3,4-dihydro-1H-isoquinoline; 885268-55-3; Tetrahydroisoquinoline ethanol derivative
EINECS	Contact for details

Quality Control

Our 2-(5-Chloro-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR) methods. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.