Description

4,4'-(5-Chloro-4-(4-Hydroxybenzyl)-1H-Imidazole-1,2-Diyl)Diphenol is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to develop next-generation medications, leveraging its specific imidazole-phenol backbone to create targeted biological activity.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block for synthesizing novel Active Pharmaceutical Ingredients (APIs).
• Research & Development: Serves as a key reagent in medicinal chemistry for drug discovery programs, especially in oncology and central nervous system (CNS) drug research.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to construct complex heterocyclic molecules for various high-value applications.
• Biochemical Research: Potential application as a precursor or ligand in the development of enzyme inhibitors or receptor modulators due to its specific pharmacophore.
• Material Science Research: Exploration as a monomer or cross-linking agent for developing specialized polymers with unique thermal or optical properties.

Basic Information

Product Name	4,4'-(5-Chloro-4-(4-Hydroxybenzyl)-1H-Imidazole-1,2-Diyl)Diphenol
CAS No.	885268-49-5
Molecular Formula	C22H17ClN2O3
Molecular Weight	392.84 g/mol
Synonyms	5-Chloro-4-(4-hydroxybenzyl)-1,2-bis(4-hydroxyphenyl)-1H-imidazole; 1,2-Bis(4-hydroxyphenyl)-5-chloro-4-[(4-hydroxyphenyl)methyl]-1H-imidazole; 4,4'-(5-Chloro-4-(4-hydroxybenzyl)-1H-imidazole-1,2-diyl)diphenol; 4-[5-Chloro-4-(4-hydroxybenzyl)-1H-imidazol-1-yl]phenol; [1,2-Bis(4-hydroxyphenyl)-5-chloro-1H-imidazol-4-yl]-(4-hydroxyphenyl)methanone (tautomer consideration); A potential intermediate for kinase inhibitor research.
EINECS	Contact for details

Quality Control

Our 4,4'-(5-Chloro-4-(4-Hydroxybenzyl)-1H-Imidazole-1,2-Diyl)Diphenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.