Description

4-(tert-Butyldimethylsilanyloxy)-1-(2-Cyanoethyl)-1H-Indole-6-Carboxylic Acid CAS NO 885266-76-2 is a key protected indole derivative, serving as a sophisticated synthetic intermediate in advanced organic chemistry. Its value lies in the strategic protection of reactive functional groups, enabling precise, multi-step synthesis of complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Organic Synthesis Research: Serves as a versatile precursor for constructing complex heterocyclic compounds and natural product analogs in academic and industrial R&D.
• Peptidomimetic Development: Facilitates the creation of indole-based peptidomimetics for probing biological pathways and drug discovery.
• Material Science Precursor: Potential use in the synthesis of specialized organic electronic materials and dyes.

Basic Information

Product Name	4-(tert-Butyldimethylsilanyloxy)-1-(2-Cyanoethyl)-1H-Indole-6-Carboxylic Acid
CAS No.	885266-76-2
Molecular Formula	C₁₈H₂₄N₂O₃Si
Molecular Weight	344.49 g/mol
Synonyms	4-[(tert-Butyldimethylsilyl)oxy]-1-(2-cyanoethyl)-1H-indole-6-carboxylic acid; 4-(TBDMSO)-1-(2-cyanoethyl)-1H-indole-6-carboxylic acid; 1H-Indole-6-carboxylic acid, 4-[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-(2-cyanoethyl)-; 4-(tert-Butyldimethylsiloxy)-1-(2-cyanoethyl)indole-6-carboxylic acid; 6-Carboxy-4-(tert-butyldimethylsiloxy)-1-(2-cyanoethyl)indole; TBDMS-protected indole-6-carboxylic acid derivative; CAS 885266-76-2
EINECS	Contact for details

Quality Control

Our production of 4-(tert-Butyldimethylsilanyloxy)-1-(2-Cyanoethyl)-1H-Indole-6-Carboxylic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a quality management system and can provide material suitable for research and development under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.