Description

4-(Boc-Amino)Indole-3-Carboxylic Acid is a high-purity, protected indole derivative that serves as a critical building block in modern organic synthesis. Its value lies in the orthogonal protection of the amino group, allowing for precise, sequential reactions in complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Peptide Mimetics & Conjugation: Used to incorporate the indole scaffold into peptide backbones or for bioconjugation strategies in drug discovery.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Academic & R&D: Fundamental reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	4-(Boc-Amino)Indole-3-Carboxylic Acid
CAS No.	885266-66-0
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	1H-Indole-3-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-; 4-[(tert-Butoxycarbonyl)amino]-1H-indole-3-carboxylic acid; Boc-4-aminoindole-3-carboxylic acid; 4-(Boc-amino)-1H-indole-3-carboxylic acid; N-Boc-4-aminoindole-3-carboxylic acid; tert-Butyl (3-carboxy-1H-indol-4-yl)carbamate; 4-(tert-Butoxycarbonylamino)indole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(Boc-Amino)Indole-3-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.