Description

4-Bromo-1-Methylindolin-2-One is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific brominated indolinone motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides that require a halogenated indolinone core structure.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport or host materials in the development of next-generation display technologies.
• Material Science Research: Employed in the synthesis of novel organic semiconductors and functional polymers with tailored electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Item	Details
Product Name	4-Bromo-1-Methylindolin-2-One
CAS No.	884855-68-9
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	4-Bromo-1-methyl-2-indolinone; 1-Methyl-4-bromoindolin-2-one; 4-Bromo-1-methylindolin-2-one; 2H-Indol-2-one, 4-bromo-1,3-dihydro-1-methyl-; 4-Bromo-1-methyl-2-oxindole; 1-Methyl-4-bromo-2-oxindole; 4-Bromo-N-methylisatin; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methylindolin-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring adherence to cGMP, ISO 9001, and other relevant regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.