Description

5-(3-Fluorobenzyl)-1,3-Thiazol-2-Amine is a high-purity, fluorinated heterocyclic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure imparts desirable biological and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Used in the design and synthesis of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science Precursor: Potential intermediate for synthesizing specialized ligands, catalysts, or monomers for advanced polymeric materials.
• Academic & Contract Research: Essential for fundamental organic chemistry research, methodology development, and custom synthesis projects in academic and CRO (Contract Research Organization) settings.

Basic Information

Item	Details
Product Name	5-(3-Fluorobenzyl)-1,3-Thiazol-2-Amine
CAS No.	884497-40-9
Molecular Formula	C10H9FN2S
Molecular Weight	208.26 g/mol
Synonyms	2-Amino-5-[(3-fluorophenyl)methyl]-1,3-thiazole; 5-[(3-Fluorophenyl)methyl]-1,3-thiazol-2-amine; 2-Thiazolamine, 5-[(3-fluorophenyl)methyl]-; 5-(3-Fluorobenzyl)thiazol-2-amine; 5-(3-Fluorobenzyl)-2-aminothiazole; 884497-40-9; 5-(3-Fluorobenzyl)-1,3-thiazol-2-ylamine
EINECS	Contact for details

Quality Control

Our 5-(3-Fluorobenzyl)-1,3-Thiazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP for early-phase pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.