Description

6-(Trifluoromethyl)-3-Methylindole is a high-value, multi-functional indole derivative distinguished by its trifluoromethyl substituent. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex molecules. It is essential for R&D and production in the pharmaceutical, agrochemical, and material science industries, where its unique fluorine-containing structure imparts desirable properties like enhanced metabolic stability and lipophilicity to final products.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science: Serves as a precursor for functional materials, including organic semiconductors, liquid crystals, and specialty polymers.
• Chemical Research: An important building block in medicinal chemistry and organic synthesis for constructing complex heterocyclic frameworks.
• Fluorine Chemistry: A valuable reagent for introducing the CF3 group into target molecules, a common strategy in modern drug design.

Basic Information

Product Name	6-(Trifluoromethyl)-3-Methylindole
CAS No.	884494-59-1
Molecular Formula	C10H8F3N
Molecular Weight	199.17 g/mol
Synonyms	3-Methyl-6-(trifluoromethyl)-1H-indole; 6-(Trifluoromethyl)-3-methyl-1H-indole; 1H-Indole, 3-methyl-6-(trifluoromethyl)-; 3-Methyl-6-trifluoromethylindole
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and MS analysis, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.