Description

2-Bromo-3-Fluoro-4-Picoline is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A versatile scaffold for custom synthesis projects and scale-up manufacturing for clients.

Basic Information

Product Name	2-Bromo-3-Fluoro-4-Picoline
CAS No.	884494-37-5
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Bromo-3-fluoro-4-methylpyridine; 4-Methyl-2-bromo-3-fluoropyridine; 3-Fluoro-2-bromo-4-picoline; 2-Bromo-3-fluoro-4-methylpyridine; 4-Picoline, 2-bromo-3-fluoro-; 884494-37-5; 2-Br-3-F-4-picoline
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Fluoro-4-Picoline is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.