Description

Cyclopropanemethanol, 2,2-Dimethyl-1-(4-Methylphenyl)- is a specialized organic compound featuring a cyclopropane ring substituted with a hydroxymethyl group and a p-tolyl moiety, making it a valuable chiral building block in advanced synthesis. Its unique sterically hindered structure is critical for developing novel active pharmaceutical ingredients (APIs) and fine chemicals with specific stereochemical requirements. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its cyclopropane structure can impart unique biological activity.
• Ligand & Catalyst Development: Acts as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Monomer: Explored as a building block for specialty polymers and advanced materials requiring rigid, bulky side chains.
• Academic & Process Chemistry: Employed in research laboratories for methodological studies and route scouting in complex molecule construction.
• Flavor & Fragrance Precursor: Potential use in synthesizing high-value aroma chemicals with complex woody or amber notes.

Basic Information

Product Name	Cyclopropanemethanol, 2,2-Dimethyl-1-(4-Methylphenyl)-
CAS No.	884091-45-6
Molecular Formula	C13H18O
Molecular Weight	190.28 g/mol
Synonyms	2,2-Dimethyl-1-(4-methylphenyl)cyclopropanemethanol; 1-(4-Methylphenyl)-2,2-dimethylcyclopropanemethanol; (1-(p-Tolyl)-2,2-dimethylcyclopropyl)methanol; α,α-Dimethyl-4-methylbenzenepropanal Cyclopropane Homolog; p-Tolyl-2,2-dimethylcyclopropylcarbinol
EINECS	Contact for details

Quality Control

Our Cyclopropanemethanol, 2,2-Dimethyl-1-(4-Methylphenyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and impurity profiles is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.