Description

3-(4-Methylpiperazine-1-Carbonyl)Phenylboronic Acid, Pinacol Ester is a sophisticated boronic ester derivative, a key intermediate in modern synthetic chemistry. Its primary value lies in its role as a protected boronic acid, offering enhanced stability and handling characteristics for critical cross-coupling reactions. This high-purity building block is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules via Suzuki-Miyaura coupling.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing aryl and heteroaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air-tolerant organoboron reagent for forming carbon-carbon bonds between aromatic rings, a cornerstone of medicinal chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-(4-Methylpiperazine-1-Carbonyl)Phenylboronic Acid, Pinacol Ester
CAS No.	883738-38-3
Molecular Formula	C19H29BN2O3
Molecular Weight	344.26 g/mol
Synonyms	[3-(4-Methyl-1-piperazinyl)carbonyl]phenylboronic acid pinacol ester; Pinacol [3-(4-methylpiperazine-1-carbonyl)phenyl]boronate; 3-(N-Methylpiperazine-1-carbonyl)benzeneboronic acid pinacol ester; (3-((4-Methylpiperazine-1-carbonyl)phenyl)boronic acid pinacol ester; B-[3-(4-Methyl-1-piperazinyl)carbonyl]phenylboronic acid pinacol ester; 883738-38-3; Boronic acid, B-[3-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our production of 3-(4-Methylpiperazine-1-Carbonyl)Phenylboronic Acid, Pinacol Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.