Description

2-Chloro-1-(6-Fluoro-1H-Indol-3-Yl)-Ethanone is a high-value fluorinated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloroacetyl and fluoroindole moieties, makes it an essential building block for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of novel bioactive molecules, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those with indole-based scaffolds for neurological and oncological targets.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products, leveraging its fluorinated heterocyclic structure.
• Organic Synthesis Building Block: Serves as a versatile electrophile for constructing complex molecules in academic and industrial research settings.
• Material Science Research: Potential intermediate for synthesizing specialty polymers or organic electronic materials due to its conjugated system.
• Biochemical Probe Development: Utilized in creating labeled compounds or inhibitors for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Chloro-1-(6-Fluoro-1H-Indol-3-Yl)-Ethanone
CAS No.	883546-72-3
Molecular Formula	C10H7ClFNO
Molecular Weight	211.62 g/mol
Synonyms	2-Chloro-1-(6-fluoro-1H-indol-3-yl)ethanone; 3-Acetyl-6-fluoroindole-2-chloride; 6-Fluoro-3-(chloroacetyl)indole; 2-Chloro-1-(6-fluoroindol-3-yl)ethan-1-one; 883546-72-3; 6-Fluoro-3-chloroacetylindole; α-Chloro-6-fluoro-3-acetylindole
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(6-Fluoro-1H-Indol-3-Yl)-Ethanone is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. We adhere to ISO 9001 standards, and our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.