Description

1-(2-Hydroxy-3-Morpholin-4-Yl-Propyl)-1H-Indole-3-Carbaldehyde is a sophisticated indole-based aldehyde derivative, characterized by its morpholine and hydroxypropyl substituents. This compound serves as a critical advanced intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and oncological pathways. It is essential for research institutions, contract research organizations (CROs), and pharmaceutical development companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Chemical Biology Probe Development: Used to create molecular probes for studying enzyme function and receptor interactions.
• Organic Synthesis Research: Serves as a versatile precursor for constructing complex heterocyclic frameworks in academic and industrial R&D.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial production of active pharmaceutical ingredients (APIs).
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(2-Hydroxy-3-Morpholin-4-Yl-Propyl)-1H-Indole-3-Carbaldehyde
CAS No.	883543-10-0
Molecular Formula	C16H20N2O3
Molecular Weight	288.34 g/mol
Synonyms	1H-Indole-3-carboxaldehyde, 1-[2-hydroxy-3-(4-morpholinyl)propyl]-; 1-(2-Hydroxy-3-morpholinopropyl)-1H-indole-3-carbaldehyde; 1-[2-Hydroxy-3-(morpholin-4-yl)propyl]-1H-indole-3-carbaldehyde; 3-Formyl-1-(2-hydroxy-3-morpholinopropyl)indole; 883543-10-0; UNII-7W3M1C4J2K; 7W3M1C4J2K
EINECS	Contact for details

Quality Control

Our production of 1-(2-Hydroxy-3-Morpholin-4-Yl-Propyl)-1H-Indole-3-Carbaldehyde adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.