Description

7-(Trifluoromethyl)-1H-Indole-2-Carboxylic Acid is a high-value, multi-functional indole derivative distinguished by its trifluoromethyl group. This compound is a critical building block in modern synthetic chemistry, prized for its ability to impart desirable metabolic stability and lipophilicity to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the indole core and the properties of the CF3 group.
• Material Science Precursor: Serves as a starting material for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: An essential raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	7-(Trifluoromethyl)-1H-Indole-2-Carboxylic Acid
CAS No.	883541-39-7
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	7-(Trifluoromethyl)-1H-indole-2-carboxylic acid; 2-Carboxy-7-(trifluoromethyl)indole; 7-Trifluoromethylindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 7-(trifluoromethyl)-; 883541-39-7; 7-(Trifluoromethyl)indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 7-(Trifluoromethyl)-1H-Indole-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed HPLC/GC purity, identity confirmation (IR, NMR), and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.