Description

(5-Fluoro-1H-Indol-2-Yl)Methanamine is a high-purity fluorinated indole derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology-related therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom and indole scaffold can enhance biological activity and stability.
• Chemical Research & Development: Acts as a fundamental building block for medicinal chemists exploring structure-activity relationships (SAR) and synthesizing new chemical entities (NCEs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis or as a precursor for metal-organic frameworks (MOFs) in material science.
• Bioconjugation and Probe Synthesis: The amine functional group allows for conjugation to other molecules, making it useful for creating fluorescent probes or biochemical tools.

Basic Information

Product Name	(5-Fluoro-1H-Indol-2-Yl)Methanamine
CAS No.	883531-07-5
Molecular Formula	C9H9FN2
Molecular Weight	164.18 g/mol
Synonyms	2-(Aminomethyl)-5-fluoro-1H-indole; 5-Fluoro-1H-indole-2-methanamine; 5-Fluoro-2-indolylmethanamine; 1H-Indole-2-methanamine, 5-fluoro-; (5-Fluoroindol-2-yl)methanamine; 5-Fluoro-2-(aminomethyl)indole; 2-Aminomethyl-5-fluoroindole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) with each batch, detailing purity and impurity profiles. Quality is assured through validated analytical methods, including HPLC, GC, and NMR, to meet the stringent requirements of research and pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.