Description

5-Cyano-7-Fluoroindole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both cyano and fluoro substituents on the indole scaffold, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and receptor modulator research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators leveraging its halogenated indole core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Fluorescent Probe Development: The indole-cyano structure is valuable for synthesizing fluorescent dyes and molecular sensors for bioimaging and diagnostics.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and discovery chemistry.
• Custom Synthesis Building Block: Provides a versatile starting point for medicinal chemistry campaigns and structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Cyano-7-Fluoroindole
CAS No.	883500-88-7
Molecular Formula	C9H5FN2
Molecular Weight	160.15 g/mol
Synonyms	7-Fluoro-1H-indole-5-carbonitrile; 7-Fluoro-5-cyanoindole; 5-Cyano-7-fluoro-1H-indole; 1H-Indole-5-carbonitrile, 7-fluoro-; 7-Fluoroindole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Cyano-7-Fluoroindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.