Description

6-Bromo-1-(tert-Butoxycarbonyl)-1H-Indole-3-Carboxylic Acid is a high-purity, protected indole derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile and reactive intermediate for constructing complex heterocyclic frameworks. It is primarily utilized in pharmaceutical R&D and fine chemical production, particularly for the synthesis of novel drug candidates and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs, library synthesis, and exploring new chemical space in academic and industrial labs.
• Peptidomimetics & Bioconjugation: The carboxylic acid and protected amine functionalities make it suitable for constructing peptide analogs and bioconjugation linkers.

Basic Information

Product Name	6-Bromo-1-(tert-Butoxycarbonyl)-1H-Indole-3-Carboxylic Acid
CAS No.	882872-15-3
Molecular Formula	C14H14BrNO4
Molecular Weight	340.17 g/mol
Synonyms	6-Bromo-1-Boc-indole-3-carboxylic acid; 1-(tert-Butoxycarbonyl)-6-bromo-1H-indole-3-carboxylic acid; 6-Bromo-1H-indole-3-carboxylic acid, 1-(1,1-dimethylethyl) 1,1-dimethylethyl ester; Boc-6-Br-indole-3-COOH; 6-Bromoindole-3-carboxylic acid tert-butyl ester; 882872-15-3; tert-Butyl 6-bromo-3-carboxyindole-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-1-(tert-Butoxycarbonyl)-1H-Indole-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.