Description

15-Tritylmercapto-4,7,10,13-Tetraoxapentadecanoic Acid Monohydrate is a specialized organic compound featuring a trityl-protected thiol group and a polyether-linked carboxylic acid chain. This molecular architecture makes it a valuable protected intermediate and building block in sophisticated organic synthesis, particularly for the controlled introduction of thiol functionalities. It is primarily utilized by research institutions and pharmaceutical R&D departments engaged in the development of peptide mimetics, bioconjugates, and novel drug delivery systems.

Application

• Peptide Synthesis: Serves as a key protected intermediate for incorporating thiol-containing amino acid analogs or for creating disulfide bridges in peptide chains.
• Bioconjugation Chemistry: Used as a functional linker for attaching drugs, probes, or polymers to biomolecules like proteins or antibodies via thiol-maleimide or thiol-haloacetyl chemistry.
• Polymer & Material Science: Acts as a functional monomer or chain-transfer agent in the synthesis of specialized polymers with tailored surface properties or reactivity.
• Ligand & Catalyst Development: Employed in the preparation of chelating ligands or organocatalysts where the protected thiol group is crucial for metal binding or catalytic activity.
• Prodrug Design: Utilized in the construction of prodrugs where the carboxylic acid and protected thiol groups allow for targeted release mechanisms.
• Chemical Biology Research: A valuable tool for site-specific labeling and modification of biomolecules in academic and industrial research settings.

Basic Information

Product Name	15-Tritylmercapto-4,7,10,13-Tetraoxapentadecanoic Acid Monohydrate
CAS No.	882847-05-4
Molecular Formula	C34H44O7S • H2O
Molecular Weight	614.78 g/mol (Monohydrate)
Synonyms	15-(Triphenylmethylthio)-4,7,10,13-tetraoxapentadecanoic Acid Monohydrate; Trt-S-(PEG)3-CH2CH2-COOH • H2O; 3-[2-[2-[2-[2-(Tritylthio)ethoxy]ethoxy]ethoxy]ethoxy]propanoic Acid Monohydrate; 15-(Tritylthio)-3,6,9,12-tetraoxapentadecanoic Acid Monohydrate; S-Trityl-3-mercaptopropionic acid tetraethylene glycol ester; Trityl-PEG3-acid Monohydrate; S-Trityl-ω-carboxy-PEG3; 3,6,9,12-Tetraoxa-15-tritylthiopentadecanoic Acid Monohydrate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical R&D and non-GMP commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	2.5 - 4.5% (Theoretical for monohydrate: ~2.93%)
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.