Description

1H-Indole-6-Carboxylic Acid, 4-Bromo-, Methyl Ester is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology and CNS (Central Nervous System) research.
• Agrochemical Research: Used in the synthesis of new-generation herbicides and plant growth regulators leveraging the indole scaffold.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	1H-Indole-6-Carboxylic Acid, 4-Bromo-, Methyl Ester
CAS No.	882679-96-1
Molecular Formula	C10H8BrNO2
Molecular Weight	254.08 g/mol
Synonyms	4-Bromo-1H-indole-6-carboxylic acid methyl ester; Methyl 4-bromo-1H-indole-6-carboxylate; 4-Bromoindole-6-carboxylic acid methyl ester; 6-(Methoxycarbonyl)-4-bromoindole; 882679-96-1; 4-Bromo-6-(methoxycarbonyl)-1H-indole; 4-Bromo-1H-indole-6-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Indole-6-Carboxylic Acid, 4-Bromo-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.