Description

1-(Benzenesulfonyl)-3-(2,5-Dichloropyrimidin-4-Yl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole and pyrimidine-based heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in oncology and other specialized therapeutic areas. CAS No. 882562-40-5.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates, particularly for oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile chemical scaffold.
• Kinase Inhibitor Development: A valuable building block for constructing potential kinase inhibitors, given the presence of the dichloropyrimidine moiety.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	1-(Benzenesulfonyl)-3-(2,5-Dichloropyrimidin-4-Yl)-1H-Indole
CAS No.	882562-40-5
Molecular Formula	C18H10Cl2N4O2S
Molecular Weight	417.27 g/mol
Synonyms	1-(Phenylsulfonyl)-3-(2,5-dichloropyrimidin-4-yl)-1H-indole; 3-(2,5-Dichloro-4-pyrimidinyl)-1-(phenylsulfonyl)-1H-indole; 1H-Indole, 1-(benzenesulfonyl)-3-(2,5-dichloro-4-pyrimidinyl)-; 882562-40-5; 1-Benzenesulfonyl-3-(2,5-dichloropyrimidin-4-yl)indole
EINECS	Contact for details

Quality Control

Our 1-(Benzenesulfonyl)-3-(2,5-Dichloropyrimidin-4-Yl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.