Description

1-Chloro-3-Methanesulfonyl-6,6-Dimethyl-6,7-Dihydro-5H-Benzo[C]Thiophen-4-One is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic reactions, including cross-coupling, cyclization, and functional group transformations, due to its reactive chloro and methanesulfonyl groups.
• Agrochemical Research: Serves as a structural motif in the development of new herbicides, fungicides, or insecticides that leverage the benzo[c]thiophenone core.
• Material Science Research: Investigated as a potential monomer or additive for creating specialized polymers with unique electronic or thermal properties.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical entities.

Basic Information

Product Name	1-Chloro-3-Methanesulfonyl-6,6-Dimethyl-6,7-Dihydro-5H-Benzo[C]Thiophen-4-One
CAS No.	882288-28-0
Molecular Formula	C11H11ClO3S2
Molecular Weight	290.78 g/mol
Synonyms	1-Chloro-3-(methylsulfonyl)-6,6-dimethyl-6,7-dihydro-5H-benzo[c]thiophen-4-one; 6,7-Dihydro-1-chloro-3-(methylsulfonyl)-6,6-dimethyl-5H-benzo[c]thiophen-4-one; 4(5H)-Benzo[c]thiophenone, 1-chloro-6,7-dihydro-3-(methylsulfonyl)-6,6-dimethyl-; 882288-28-0; 1-Chloro-3-methanesulfonyl-6,6-dimethyl-6,7-dihydrobenzo[c]thiophen-4(5H)-one
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Methanesulfonyl-6,6-Dimethyl-6,7-Dihydro-5H-Benzo[C]Thiophen-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.