Description

1-(3-Chloro-4-Fluorophenyl)Dihydro-1H-Pyrrole-2,5-Dione is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in kinase inhibitor and anti-inflammatory agent development.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Employed in the development of advanced organic electronic materials and specialty polymers.
• Chemical Biology: Serves as a probe or linker in the design of molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	1-(3-Chloro-4-Fluorophenyl)Dihydro-1H-Pyrrole-2,5-Dione
CAS No.	882081-02-9
Molecular Formula	C10H7ClFNO2
Molecular Weight	227.62 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)pyrrolidine-2,5-dione; 3-Chloro-4-fluoro-N-(2,5-dioxopyrrolidin-1-yl)aniline; 1-(3-Chloro-4-fluorophenyl)-2,5-pyrrolidinedione; 882081-02-9; 1H-Pyrrole-2,5-dione, 1-(3-chloro-4-fluorophenyl)dihydro-; 1-(3-Chloro-4-fluorophenyl)-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-4-Fluorophenyl)Dihydro-1H-Pyrrole-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.