Description

Ethyl 3-Bromo-5-Chloro-1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical advanced pharmaceutical intermediate for modern drug discovery and development. Its complex molecular architecture, featuring bromo, chloro, and phenylsulfonyl substituents, makes it an invaluable versatile building block for synthesizing novel bioactive compounds. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides due to its bioactive indole core structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other transformations to construct complex heterocyclic systems for material science.
• Biochemical Research: Serves as a probe or inhibitor in enzymatic studies and biochemical pathway analysis.
• Material Science Precursor: Utilized in the development of organic semiconductors, dyes, and photoresponsive materials.

Basic Information

Product Name	Ethyl 3-Bromo-5-Chloro-1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate
CAS No.	881924-59-0
Molecular Formula	C17H13BrClNO4S
Molecular Weight	458.71 g/mol
Synonyms	Ethyl 3-bromo-5-chloro-1-(phenylsulfonyl)indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 3-bromo-5-chloro-1-(phenylsulfonyl)-, ethyl ester; 3-Bromo-5-chloro-1-(phenylsulfonyl)-1H-indole-2-carboxylic acid ethyl ester; 881924-59-0; Ethyl 3-bromo-5-chloro-1-(benzenesulfonyl)-1H-indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-5-Chloro-1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.