Description

Ethyl 2-(5-Bromo-2-Oxoindolin-1-Yl)Acetate is a high-purity, specialized organic compound serving as a critical building block in advanced chemical synthesis. This brominated oxindole derivative is valued for its precise molecular structure, enabling the development of novel compounds with targeted biological activity. It is primarily required by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other protein-protein interactions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological profile of oxindole-based compounds.
• Organic Synthesis Building Block: The ethyl acetate moiety and bromine atom provide handles for further functionalization via cross-coupling reactions or hydrolysis.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection, leveraging the bioactive oxindole scaffold.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl 2-(5-Bromo-2-Oxoindolin-1-Yl)Acetate
CAS No.	881608-39-5
Molecular Formula	C₁₂H₁₂BrNO₃
Molecular Weight	298.13 g/mol
Synonyms	1H-Indole-1-acetic acid, 5-bromo-2,3-dihydro-2-oxo-, ethyl ester; Ethyl (5-bromo-2-oxoindolin-1-yl)acetate; 5-Bromo-1-(carbethoxymethyl)indolin-2-one; 5-Bromo-2-oxoindoline-1-acetic acid ethyl ester; 881608-39-5; Ethyl 5-bromo-2-oxoindoline-1-acetate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-(5-Bromo-2-Oxoindolin-1-Yl)Acetate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with exacting standards suitable for research and development applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with each shipment to guarantee reliable and consistent performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.