Description

6-Bromo-1-Phenylsulfonyl-3-Chlorosulfonylindol is a high-value, multi-functionalized indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromo and chlorosulfonyl substituents, makes it an indispensable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated indole core.
• Material Science: Serves as a monomer or functionalization agent for creating specialized polymers, dyes, and photoactive materials.
• Chemical Synthesis: Versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions due to the reactive bromine and chlorosulfonyl groups.
• Academic & Contract Research: Essential reagent for methodological development and exploring new chemical space in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	6-Bromo-1-Phenylsulfonyl-3-Chlorosulfonylindol
CAS No.	881406-31-1
Molecular Formula	C14H9BrClNO4S2
Molecular Weight	434.71 g/mol
Synonyms	1-(Phenylsulfonyl)-6-bromo-3-(chlorosulfonyl)-1H-indole; 6-Bromo-1-(phenylsulfonyl)-1H-indole-3-sulfonyl chloride; 6-Bromo-1H-indole-3-sulfonyl chloride, 1-(phenylsulfonyl)-; 3-Chlorosulfonyl-6-bromo-1-phenylsulfonylindole; 6-Bromo-1-(benzenesulfonyl)-1H-indole-3-sulfonyl chloride; 6-Bromo-1-(phenylsulfonyl)indole-3-sulfonyl chloride; BPSI-CS; 881406-31-1
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Phenylsulfonyl-3-Chlorosulfonylindol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.