Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-(4,6-Dimethoxy-1,3,5-Triazin-2-Yl)Hexahydro-2-Oxo-, (3As,4S,6Ar)- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for enabling sophisticated synthetic pathways in modern drug discovery and development, offering researchers a reliable building block for creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors working on innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and production of novel small-molecule drugs.
• Bioconjugation Reagent: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted therapies due to its reactive functional groups.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex organic molecules under GMP or non-GMP conditions.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-(4,6-Dimethoxy-1,3,5-Triazin-2-Yl)Hexahydro-2-Oxo-, (3As,4S,6Ar)-
CAS No.	881249-07-6
Molecular Formula	C17H22N6O4S
Molecular Weight	406.46 g/mol
Synonyms	N-(4,6-Dimethoxy-1,3,5-triazin-2-yl)hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; (3aS,4S,6aR)-N-(4,6-Dimethoxy-1,3,5-triazin-2-yl)hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(4,6-dimethoxy-1,3,5-triazin-2-yl)hexahydro-2-oxo-, (3aS,4S,6aR)-; CAS 881249-07-6; Advanced Triazine-Linked Biotin Derivative; Biotin-Triazine Conjugate; Activated Biotin Reagent.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Certificates of Analysis (COA) are provided with each shipment, detailing purity, identity, and impurity profiles. Quality is verified through analytical methods including HPLC, NMR, and mass spectrometry, supporting compliance with internal specifications suitable for non-GMP and GMP-grade manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.