Description

6-Bromo-4-Fluoro-2,3-Dihydro-1H-Inden-1-One is a high-value, multi-functional halogenated indanone derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both bromine and fluorine substituents on the aromatic ring fused to a ketone-containing five-membered ring, makes it an indispensable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-inflammatory agents.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the bromo-fluoro motif can enhance biological activity and environmental profile.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand & Catalyst Development: The structure can be modified to create novel chiral ligands or organocatalysts for asymmetric synthesis.
• Chemical Biology Probe Synthesis: Utilized in medicinal chemistry to create tool compounds for target validation and pathway analysis in biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Bromo-4-Fluoro-2,3-Dihydro-1H-Inden-1-One
CAS No.	881189-74-8
Molecular Formula	C9H6BrFO
Molecular Weight	229.05 g/mol
Synonyms	6-Bromo-4-fluoroindan-1-one; 4-Fluoro-6-bromo-2,3-dihydro-1H-inden-1-one; 1H-Inden-1-one, 6-bromo-4-fluoro-2,3-dihydro-; 6-Bromo-4-fluoro-2,3-dihydroinden-1-one; 6-Bromo-4-fluoroindanone
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Fluoro-2,3-Dihydro-1H-Inden-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive analytical data including HPLC purity, NMR (1H, 13C, 19F), and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available for every batch and provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.