Description

Methyl 2-Amino-5-Ethyl-4-Methyl-3-Thiophenecarboxylate CAS NO 881041-08-3 is a high-purity, multi-substituted thiophene derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring sophisticated heterocyclic chemistry, such as medicinal chemistry for drug discovery and crop protection science for novel active ingredients, rely on this high-quality intermediate for its structural specificity and synthetic utility.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the thiophene core for enhanced biological activity.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized heterocyclic dyes and pigments with unique colorfastness and optical properties.
• Chemical Research & Development: A valuable scaffold for medicinal chemists and process chemists in lead optimization, structure-activity relationship (SAR) studies, and route scouting.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	Methyl 2-Amino-5-Ethyl-4-Methyl-3-Thiophenecarboxylate
CAS No.	881041-08-3
Molecular Formula	C9H13NO2S
Molecular Weight	199.27 g/mol
Synonyms	Methyl 2-Amino-5-Ethyl-4-Methylthiophene-3-Carboxylate; 3-Thiophenecarboxylic acid, 2-amino-5-ethyl-4-methyl-, methyl ester; 2-Amino-5-ethyl-4-methyl-3-thiophenecarboxylic acid methyl ester; 5-Ethyl-4-methyl-2-aminothiophene-3-carboxylic acid methyl ester; Methyl 5-ethyl-4-methyl-2-aminothiophene-3-carboxylate; AMETC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5-Ethyl-4-Methyl-3-Thiophenecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we support customer audits and regulatory documentation for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.