Description

4-(4-Bromo-5-Methyl-2-Thienyl)-1,3-Thiazole is a high-value, heterocyclic organic compound featuring a brominated thiophene core fused with a thiazole ring. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological or electronic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene-thiazole system.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a core structure for designing fluorescent tags or molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific brominated heterocycle.

Basic Information

Product Name	4-(4-Bromo-5-Methyl-2-Thienyl)-1,3-Thiazole
CAS No.	881040-57-9
Molecular Formula	C8H6BrNS2
Molecular Weight	260.17 g/mol
Synonyms	4-(4-Bromo-5-methyl-2-thienyl)thiazole; 4-(4-Bromo-5-methylthiophen-2-yl)-1,3-thiazole; 4-(4-Bromo-5-methyl-2-thienyl)thiazole; 2-(4-Bromo-5-methyl-2-thienyl)-1,3-thiazole; 4-(4-Bromo-5-methylthien-2-yl)thiazole; Thiazole, 4-(4-bromo-5-methyl-2-thienyl)-; 881040-57-9
EINECS	Contact for details

Quality Control

Our production of 4-(4-Bromo-5-Methyl-2-Thienyl)-1,3-Thiazole adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and tested against comprehensive specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support development and commercial projects with quality systems designed to meet cGMP and ISO standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.